Factor X Deficiency


Research/IND Treatment Protocols

Bio Products Laboratory (BPL) is currently sponsoring 3 clinical trials to study BPL’s high-purity, plasma-derived FX product Coagadex® in certain clinical settings-

  1. A study to investigate BPL’s factor X in the prophylaxis of bleeding in children <12 years; Available from: https://clinicaltrials.gov/ct2/show/NCT01721681
  2. Data collection to investigate compassionate use with FACTOR X: a multicenter, retrospective data collection study on the use of BPL’s high purityfactor X in the treatment of patients with hereditary factor X deficiency: National Health Service Health Research Authority – Ten05; Available from: http://www.hra.nhs.uk/news/research-summaries/data-collection-to-investigate-compassionate-use-with-factor-x/
  3. Post-marketing registry of use of Coagadex® for surgical procedures – US Food and Drug Administration. Biologics license application approval for coagulation factor X (human); Available from: https://www.fda.gov/download/BiologicsBloodVaccines/BloodBloodProducts/ApprovedProducts/LicensedProductsBLAs/FractionatedPlasmaProducts/UCM468124.pdf